The Most Important Step to Ease Your Interruptions:
When it comes to interruptions there is a never-ending realm of possible actions.
The KEY with ALL interruptions is to PAUSE before you take any action.
STOP, take a deep breath and evaluate the situation.
Ask yourself, "Is this interruption more important than what I'm currently doing?"
What you choose to do depends on many things including WHO the interrupter is, whether it's URGENT or not, whether the interrupter is a repeat offender, whether it benefits YOU or not, whether the interruption is valid, whether you are in a state of flow etc. And if you find you are actually welcoming interruptions AND not getting things done, you may need to have a deeper review around your motivation.
Finally remember, respect is essential - whether you're dealing with yourself or someone else.
It can help to think of it like this: Say "Yes" to the person, but "No" to the task.